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Uses and Benefits of Acetyl L Carnitine
By: Raj Khatri
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Other Benefits of Acetyl-L-Carnitine
- Protects and Enhances Mitochondrial Function
- Enhances Immune Function and IGF-1 levels
- Protects against the loss and reduction in axonal transport of substance P
- Reduces HPA axis hyperactivity
- Increases hippocampal synaptic contact zones
- Protects against stress-induced neuroendocrine changes
- Enhances long-term memory
- Increases learning capacity
- Prevents age-related memory deterioration
- Helps maintain a normal number of both axosomatic synapses and giant bouton vesicles
- Increases membrane fluidity and counters the increase in membrane viscosity seen both in aging and in neuronal lipid peroxidation
- Protects cell membranes from physical stress
- Reduces lipofuscin accumulation in neurons
- Helps neurons remain energetic by using alternate energy sources such as lipids and ketones
- Increases the efficiency of neuronal transmission
- Protects against ischemia/reperfusion induced cellular damage and lowers lactic acid levels and speeds recovery from ischemic events
- Protects neuronal RNA from damage
- Helps maintain cholinergic transmission between neurons
- Protects against DNA breakage
We studied the effects of acetyl-L-carnitine on pain in 16 HIV+ patients affected by painful distal symmetrical neuropathy. Patients were treated with 0.5-1 gr per day of acetyl-L-carnitine either i.m. or i.v. for 3 weeks. Pain intensity was measured before and after the treatment by the Huskisson's analogic scale. Ten patients (62.5%)reported an improvement of symptoms, five patients (31.25%) were unchanged, one patient worsened. The results of this open study show that acetyl-L-camitine can have a role in the treatment of pain in distal symmetrical polyneuropathy related to HIV infection. However, further double-blind, placebo-controlled studies are needed to confirm these preliminary results.
Raj Khatri
For more information please visit
http://www.acetyl-carnitine.com
raaj81@gmail.com
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