Uses and Benefits of Acetyl L Carnitine

Carnitine Nutrition can play an important role in promoting brain wellness. The older we are, the more likely we are to suffer from cognitive loss. While some survive into their sixth and seventh decades with good mental function, this becomes less likely as we age further. Decline is almost universal in at least one cognitive area among those over .

Certain nutrients have also undergone examination for their role in promoting brain health in older adults. One of the most extensively researched nutrients for its role in promoting brain wellness is Acetyl-L-Carnitine (ALCAR). ALCAR has demonstrated marked positive effects on brain aging, both from a preventive and therapeutic standpoint.

There is also a great deal of evidence that age-related memory loss is cholinergic in nature. Therefore, maintaining healthy acetylcholine levels must be the centerpiece of any brain antiaging strategy. ALCAR levels decline markedly as we age, even in healthy adults. Restoring ALCAR levels to those seen in twenty-year olds may be desirable for older adults. Declining ALCAR levels may in fact be one of the causes of the cognitive decline seen with aging.

What other benefits does carnitine have?

Improved cognitive function - ALCAR plays a strong role in the brain in many ways, and has beneficial effects in many conditions including Alzheimer's and Parkinson's. Studies in aged rodents show markedly improved memory and learning capacities, , while studies in younger rodents show a variety of promising effects as well. Other rodent studies have shown that ALCAR significantly protects the brain against a variety of stresses, such as ischemia and repurfusion and mitochondrial uncoupling. It also protects against peripheral nerve trauma, "almost eliminating neuron loss, and in vitro neuronal apoptosis. ALCAR also increases levels of dopamine, amino acids, and acetylcholine in the brain, as well as facilitating cholinergic activity.

Cardiovascular benefits - The carnitine have considerable potential in the treatment of cardiovascular disease. Rodent studies with L-carnitine have shown decreased triglyceride and cholesterol levels and protection against arrhythmia and ischemia, and a study with ALCAR found a reversal of the age-related decline in mitochondrial function in the heart.

Improved hearing and visual function - Two animal studies indicate a significant reduction in noise-induced and age-induced hearing loss with ALCAR. One measured outer hair cell (OHC) density after three weeks of noise exposure, and found less than a 10% reduction with ALCAR as opposed to 60% with placebo, and noise induced threshold shifts were less than 10 dB in the ALCAR group as opposed to 30-35 dB with placebo. A six-week study with aged rats found ALCAR to improve auditory thresholds by upregulating mitochondrial function and reducing oxidative stress.

[ Continued on next page ==> ]